Mogroside III-E | TN1936

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€263.00 - €493.00
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TMC-TN1936
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Product Overview

Mogroside III-E | TN1936 | TargetMol Chemicals

CAS: 88901-37-5

Smiles: [H][C@]12CC[C@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)C(C)(C)C1=CC[C@@]1([H])[C@]3(C)CC[C@H]([C@H](C)CC[C@@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C(C)(C)O)[C@@]3(C)C[C@@H](O)[C@@]21C

Formula: C48H82O19

Pathway: Apoptosis|||Immunology/Inflammation

Target: IL Receptor|||TNF|||TLR

Receptor: N/A

Bioactivity: Mogroside III-E is a cucurbitane-type compound isolated from Siraitia grosvenorii, has anti-inflammatory activity, it attenuates LPS-induced acute lung injury in mice partly through regulation of the TLR4/MAPK/NF-κB axis via AMPK activation. It also has anti-fibrotic activity, it reduces pulmonary fibrosis through Toll-Like receptor 4 pathways.

Molecular Weight: 963, 165

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