Momelotinib Mesylate | T15037

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TMC-T15037
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Product Overview

Momelotinib Mesylate | T15037 | TargetMol Chemicals

CAS: 1056636-07-7

Smiles: CS(O)(=O)=O.O=C(NCC#N)c1ccc(cc1)-c1ccnc(Nc2ccc(cc2)N2CCOCC2)n1

Formula: C24H26N6O5S

Pathway: Angiogenesis|||Chromatin/Epigenetic|||JAK/STAT signaling|||Stem Cells

Target: JAK

Receptor: N/A

Bioactivity: Momelotinib Mesylate is an ATP-competitive JAK1/JAK2 inhibitor (IC50: 11 nM/18 nM). It has 10-fold selectivity versus JAK3.

Molecular Weight: 510, 57

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