Product Overview
Momordin Ic | T3410 | TargetMol Chemicals
CAS: 96990-18-0
Smiles: CC1(C)CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O[C@@H]6O[C@H]([C@H](O)[C@@H](O[C@H]7OC[C@H](O)[C@@H](O)[C@@H]7O)[C@@H]6O)C(O)=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2C1)C(O)=O
Formula: C41H64O13
Pathway: Apoptosis|||MAPK|||PI3K/Akt/mTOR signaling
Target: Apoptosis|||MAPK|||PI3K
Receptor: N/A
Bioactivity: Momordin Ic might represent a potential anticancer activity, by inducing apoptosis through oxidative stress-regulated mitochondrial dysfunction involving the MAPK and PI3K-mediated iNOS and HO-1 pathways. Also, Momordin Ic accelerates gastrointestinal transit partially by stimulating synthesis of 5-HT to act through 5-HT(2), which, in turn, increases synthesis of prostaglandins.
Molecular Weight: 764, 95
