Product Overview
Monocrotaline | T2803 | TargetMol Chemicals
CAS: 315-22-0
Smiles: C[C@H]1C(=O)O[C@@H]2CCN3CC=C(COC(=O)[C@](C)(O)[C@]1(C)O)[C@H]23
Formula: C16H23NO6
Pathway: Stem Cells
Target: TGF-beta/Smad
Receptor: N/A
Bioactivity: Monocrotaline is a pyrrolizidine alkaloid and a toxic plant constituent that poisons livestock and humans through the ingestion of contaminated grains and other foods. The alkaloid causes pulmonary artery hypertension, right ventricular hypertrophy, and pathological changes in the pulmonary vasculature. Significant attenuation of the cardiopulmonary changes is noted after oral magnesium treatment.
Molecular Weight: 325, 361
