Product Overview
Monomethyl auristatin E | T6897 | TargetMol Chemicals
CAS: 474645-27-7
Smiles: CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@H](C)[C@@H](O)c1ccccc1)OC)N(C)C(=O)[C@@H](NC(=O)[C@@H](NC)C(C)C)C(C)C
Formula: C39H67N5O7
Pathway: Apoptosis|||Cytoskeletal Signaling
Target: Apoptosis|||Microtubule Associated
Receptor: N/A
Bioactivity: Monomethyl auristatin E (MMAE), an antimitotic agent, inhibits cell division by blocking the polymerization of tubulin and also has inhibition of antibody-drug conjugates (ADCs) activity.
Molecular Weight: 717, 993