Product Overview
Morachalcone A | TN4580 | TargetMol Chemicals
CAS: 76472-88-3
Smiles: CC(C)=CCc1c(O)ccc(C(=O)\C=C\c2ccc(O)cc2O)c1O
Formula: C20H20O5
Pathway: Proteases/Proteasome
Target: Tyrosinase
Receptor: N/A
Bioactivity: Morachalcone A displays significant tyrosinase inhibitory activity (IC50, 0.013 uM); it also exerts strong pancreatic lipase inhibition with IC 50 value of 6.2 uM. Morachalcone A exhibits neuroprotective effects on HT22-immortalized hippocampal cells against glutamate-induced oxidative stress, with EC50 values of 35.5±2.1 uM. It exhibits potent inhibitory activity on nitric oxide production in RAW264.7 LPS-activated mouse macrophage cells with IC50 value of 16.4 microM.
Molecular Weight: 340, 4