Product Overview
Motesanib | T2288 | TargetMol Chemicals
CAS: 453562-69-1
Smiles: CC1(C)CNc2cc(NC(=O)c3cccnc3NCc3ccncc3)ccc12
Formula: C22H23N5O
Pathway: Angiogenesis|||Tyrosine Kinase/Adaptors
Target: VEGFR|||c-Kit
Receptor: N/A
Bioactivity: Motesanib is an orally bioavailable receptor tyrosine kinase inhibitor with potential antineoplastic activity. AMG 706 selectively targets and inhibits vascular endothelial growth factor (VEGFR), platelet-derived growth factor (PDGFR), Kit, and Ret receptors, thereby inhibiting angiogenesis and cellular proliferation.
Molecular Weight: 373, 46
