Product Overview
MRTX1133 | T9303 | TargetMol Chemicals
CAS: 2621928-55-8
Smiles:
Formula: N/A
Pathway: GPCR/G Protein|||MAPK
Target: Ras
Receptor: N/A
Bioactivity: MRTX1133 is a potent, selective, noncovalent KRASG12D inhibitor. It has picomolar binding affinity, single-digit nanomolar activity in cellular assays. In addition, it has significant in vivo efficacy in tumor models harboring KRASG12D mutations.
Molecular Weight: N/A