Product Overview
MS4078 | T16153 | TargetMol Chemicals
CAS: 2229036-62-6
Smiles: CC(C)Oc1cc(C2CCN(CC(=O)NCCNc3cccc4C(=O)N(C5CCC(=O)NC5=O)C(=O)c34)CC2)c(C)cc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1
Formula: C45H52ClN9O8S
Pathway: Angiogenesis|||Tyrosine Kinase/Adaptors
Target: ALK
Receptor: N/A
Bioactivity: MS4078 is an inhibitor and aplastic lymphoma kinase (ALK) PROTAC (degrader) based on Cereblon ligand, with a Kd of 19 nM for binding affinity to ALK.
Molecular Weight: 914, 48