Product Overview
MS417 | T16154 | TargetMol Chemicals
CAS: 916489-36-6
Smiles: COC(=O)C[C@@H]1N=C(c2c(C)c(C)sc2-n2c(C)nnc12)c1ccc(Cl)cc1
Formula: C20H19ClN4O2S
Pathway: Chromatin/Epigenetic|||Microbiology/Virology|||Proteases/Proteasome
Target: Epigenetic Reader Domain|||HIV Protease
Receptor: N/A
Bioactivity: MS417 is an inhibitor of BET-specific BRD4(BRD4-BD1 and BRD4-BD2 with IC50s of 30, 46 nM and Kds of 36.1, 25.4 nM, respectively), with weak selectivity at CBP BRD with IC50 of 32.7 μM.
Molecular Weight: 414, 91