Product Overview
Myricanone | TN4604 | TargetMol Chemicals
CAS: 32492-74-3
Smiles: COc1c(O)c2CCCCC(=O)CCc3ccc(O)c(c3)-c(c2)c1OC
Formula: C21H24O5
Pathway: Apoptosis|||Cytoskeletal Signaling|||Immunology/Inflammation|||JAK/STAT signaling|||Metabolism|||NF-Κb|||Proteases/Proteasome|||Stem Cells
Target: BCL|||HSP|||NF-κB|||ROS|||Caspase|||STAT
Receptor: N/A
Bioactivity: Myricanone has antioxidant, and anticancer activities, it has apoptosis-promoting ability by triggering caspase activation, and suppression of cell proliferation by down-regulation of NF-κB and STAT3 signalling cascades. Myricanone shows in vitro testosterone 5alpha-reductase inhibitory activity and in vivo anti-androgenic activity using growth of flank organ in castrated Syrian hamsters and/or hair regrowth after shaving in testosterone-treated C57Black/6CrSlc mice.
Molecular Weight: 356, 4