Product Overview
Myriocin | T16165 | TargetMol Chemicals
CAS: 35891-70-4
Smiles: CCCCCCC(=O)CCCCCC\C=C\C[C@@H](O)[C@H](O)[C@@](N)(CO)C(O)=O
Formula: C21H39NO6
Pathway: Cell Cycle/Checkpoint
Target: Chk
Receptor: N/A
Bioactivity: Myriocin is a fungal metabolite isolated from Myriococcum albomyces, Isaria sinclairi and Mycelia sterilia. Myriocin also is an effective inhibitor of serine-palmitoyl-transferase (SPT) and a key enzyme in de novo synthesis of sphingolipids. Myriocin strongly inhibits replication of both the subgenomic HCV-1b replicon and the JFH-1 strain of genotype 2a infectious HCV. It has an IC50 of 3.5 μg/mL for inhibiting HCV infection.
Molecular Weight: 401, 544
