Product Overview
Myristicin | T9113 | TargetMol Chemicals
CAS: 607-91-0
Smiles: COc1cc(CC=C)cc2OCOc12
Formula: C11H12O3
Pathway: Apoptosis|||Chromatin/Epigenetic|||DNA Damage/DNA Repair|||GPCR/G Protein|||Immunology/Inflammation|||Membrane transporter/Ion channel|||Metabolism|||Microbiology/Virology|||Neuroscience|||Proteases/Proteasome
Target: IL Receptor|||Anti-infection|||BCL|||P450|||PARP|||5-HT Receptor|||Caspase|||GABA Receptor|||NO Synthase
Receptor: N/A
Bioactivity: Myristicin is a natural product found in spices and umbelliferous plants. Myristicin has anti-cholinergic, antibacterial, and hepatoprotective effects, it also has anti-inflammatory properties related with its inhibition of NO, cytokines, chemokines, and growth factors in dsRNA-stimulated macrophages via the calcium pathway. Myristicin may antagonize the anxiolytic effects of midazolam, increase anxiety, and affect motor movements. Myristicin can induce apoptosis as characterised by alterations in the mitochondrial membrane potential, cytochrome c release, caspase-3 activation, PARP-cleavage and DNA fragmentation.
Molecular Weight: 192, 214
