N-Desalkylflurazepam | T40366

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TMC-T40366
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Product Overview

N-Desalkylflurazepam | T40366 | TargetMol Chemicals

CAS: 2886-65-9

Smiles: Fc1ccccc1C1=NCC(=O)Nc2ccc(Cl)cc12

Formula: C15H10ClFN2O

Pathway: Membrane transporter/Ion channel|||Metabolism

Target: Calcium Channel

Receptor: N/A

Bioactivity: N-Desalkylflurazepam (Norfludiazepam) is a long-acting metabolite of benzodiazepine compounds, such as Flurazepam. N-Desalkylflurazepam inhibits L-type voltage-gated calcium channels with IC 50 values of 55 μM and 37 μM for Ca v 1.2 and Ca v 1.3, respectively [1] [2] .

Molecular Weight: 288, 71

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