N-Formyl-Met-Leu-Phe-Lys | TP1168

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Product Overview

N-Formyl-Met-Leu-Phe-Lys | TP1168 | TargetMol Chemicals

CAS: 67247-11-4

Smiles: CSCC[C@H](NC=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(O)=O

Formula: C27H43N5O6S

Pathway: Others

Target: Others

Receptor: N/A

Bioactivity: N-Formyl-Met-Leu-Phe-Lys (fMLFK) is a peptide, acts as a potent and selective agonist of FPR1, with EC50s of 3.5 nM, 6.7 μM and 0.88 μM for FPR1, FPR2 and FPR2-D2817.32G, respectively.Chemotactic peptide (fMLFK) binds specifically to receptors on leukocyte membranes. Uptake of chemotactic peptides can contribute to quantitative assessment of neutrophils in localized inflammatory processes and is independent of associated edema formation or microcirculatory compromise.

Molecular Weight: 565, 73

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