N3-PEG3-vc-PAB-MMAE | T18473

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TMC-T18473
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N3-PEG3-vc-PAB-MMAE | T18473 | TargetMol Chemicals

CAS: T18473

Smiles: CC[C@H](C)[C@@H]([C@@H](CC(N1[C@@H](CCC1)[C@@H]([C@@H](C)C(N[C@H](C)[C@@H](O)C2=CC=CC=C2)=O)OC)=O)OC)N(C([C@H](C(C)C)NC([C@H](C(C)C)N(C(OCC3=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCOCCOCCOCCN=[N+]=[N-])=O)=O)=O)C=C3)=O)C)=O)=O)C

Formula: C67H109N13O16

Pathway: Others

Target: Others

Receptor: N/A

Bioactivity: N3-PEG3-vc-PAB-MMAE is a synthesized drug-linker conjugate for ADC that incorporates the MMAE (a tubulin inhibitor ) and 3-unit PEG linker. N3-PEG3-vc-PAB-MMAE shows potent antitumor activity.

Molecular Weight: 1352, 66

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