Product Overview
NAE-IN-M22 | T8816 | TargetMol Chemicals
CAS: 864420-54-2
Smiles: Clc1ccc(CCNC2CCN(Cc3ccccc3)CC2)c(Cl)c1
Formula: C20H24Cl2N2
Pathway: Apoptosis|||Ubiquitination
Target: Apoptosis|||E1/E2/E3 Enzyme
Receptor: N/A
Bioactivity: NAE-IN-M22 is a selective, potent and reversible inhibitor of NEDD8 activating enzyme (NAE). NAE-IN-M22 inhibits multiple cancer cell lines and induces apoptosis in A549 cells. NAE-IN-M22 also can inhibit tumor growth in vivo.
Molecular Weight: 363, 33
