Product Overview
Nalfurafine | T41284 | TargetMol Chemicals
CAS: 152657-84-6
Smiles: CN([C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45)C(=O)\C=C\c1ccoc1
Formula: C28H32N2O5
Pathway: Endocrinology/Hormones|||GPCR/G Protein|||Neuroscience
Target: Opioid Receptor
Receptor: N/A
Bioactivity: Nalfurafine is an effective and selective agonist of G protein-biased κ-opioid receptor with high translational potential. Nalfurafine enhances the therapeutic potential of MOR-targeting analgesics and can be used for uremic pruritis treatment studies.
Molecular Weight: 476, 573
