Product Overview
Nantenine | TN4624 | TargetMol Chemicals
CAS: 2565-01-7
Smiles: COc1cc2CCN(C)[C@H]3Cc4cc5OCOc5cc4-c(c1OC)c23
Formula: C20H21NO4
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: Nantenine is an acetylcholinesterase inhibitor, it functions as an effective antagonist against a wide range of MDMA-induced effects in mice. Nantenine has anticonvulsant effect, which seems attributable to its stimulation and the resultant decrease of Ca2+-influx into the cell. (+)-Nantenine has antagonistic activities on alpha1-adrenoceptors, alpha2-adrenoceptors and 5-HT2A receptors in pithed rats. Nantenine displays cytotoxicity against SMMC-7721 with the IC50 value of 70.08 ± 4.63 uM.
Molecular Weight: 339, 38