Naproxen etemesil | T16272

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TMC-T16272
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Product Overview

Naproxen etemesil | T16272 | TargetMol Chemicals

CAS: 385800-16-8

Smiles: COc1ccc2cc(ccc2c1)[C@H](C)C(=O)OCCS(C)(=O)=O

Formula: C17H20O5S

Pathway: Metabolism

Target: PDE

Receptor: N/A

Bioactivity: Naproxen is a COX-1 and COX-2 inhibitor (IC50s: 8.72 and 5.15 μM, respectively in cell assay). Naproxen etemesil is a lipophilic and non-acidic prodrug of naproxen. It is hydrolyzed to pharmacologically active Naproxen once absorbed.

Molecular Weight: 336, 4

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