Product Overview
Navitoclax | T2101 | TargetMol Chemicals
CAS: 923564-51-6
Smiles: CC1(C)CCC(=C(CN2CCN(CC2)c2ccc(cc2)C(=O)NS(=O)(=O)c2ccc(N[C@H](CCN3CCOCC3)CSc3ccccc3)c(c2)S(=O)(=O)C(F)(F)F)C1)c1ccc(Cl)cc1
Formula: C47H55ClF3N5O6S3
Pathway: Apoptosis
Target: BCL
Receptor: N/A
Bioactivity: Navitoclax (ABT-263) is a potent, orally bioavailable Bcl-2 family protein inhibitor that avidly binds Bcl-2, Bcl-xL, and Bcl-W (Ki < 1 nM for all three proteins).
Molecular Weight: 974, 61
