Product Overview
NC190 sodium | T25857 | TargetMol Chemicals
CAS: 120602-99-5
Smiles: [Na+].COc1cc2nc3c4ccccc4c(O)c(C(=O)NCCN(C)C)c3nc2cc1C([O-])=O
Formula: C23H21N4NaO5
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: NC190 is an inhibitor of topoisomerase II that inhibited the growth of FM3A cells in clinical trials. NC-190 strongly inhibited the growth of FM3A cells when cultured with NC-190 for 48 h (IC50: 0.019 μg/ml). NC-190 potently suppressed DNA synthesis with 90% inhibition observed at 0.1 μg/ml of NC-190.
Molecular Weight: 456, 434
