Product Overview
NDI-091143 | T7424 | TargetMol Chemicals
CAS: 2375840-87-0
Smiles: COC(=O)c1cc(Cl)c(O)c(c1)S(=O)(=O)Nc1cc(c(F)cc1F)-c1ccccc1
Formula: C20H14ClF2NO5S
Pathway: Metabolism
Target: ATP Citrate Lyase
Receptor: N/A
Bioactivity: NDI-091143 is a potent and high-affinity human ATP-citrate lyase (ACLY) inhibitor with an IC50 of 2.1 nM (ADP-Glo assay), indirectly disrupting citrate binding via an unexpected mechanism of inhibition.
Molecular Weight: 453, 84
