Nebicapone | T16279

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TMC-T16279
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Product Overview

Nebicapone | T16279 | TargetMol Chemicals

CAS: 274925-86-9

Smiles: Oc1cc(cc(c1O)[N+]([O-])=O)C(=O)Cc1ccccc1

Formula: C14H11NO5

Pathway: Others

Target: Others

Receptor: N/A

Bioactivity: Nebicapone is a reversible catechol-O-methyltransferase (COMT) inhibitor and is mainly metabolized by glucuronidation. Nebicapone is mainly peripherally acting inhibitor that decreases the biotransformation of L-DOPA to 3-O-methyl-DOPA by inhibition of COMT. It is the potential for the treatment of Parkinson's disease.

Molecular Weight: 273, 244

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