Product Overview
Necrostatin-1 | T1847 | TargetMol Chemicals
CAS: 4311-88-0
Smiles: CN1C(=S)NC(Cc2c[nH]c3ccccc23)C1=O
Formula: C13H13N3OS
Pathway: Apoptosis|||Autophagy|||Cell Cycle/Checkpoint|||Metabolism|||NF-Κb
Target: Indoleamine 2, 3-Dioxygenase (IDO)|||Ferroptosis|||Autophagy|||RIP kinase
Receptor: N/A
Bioactivity: Necrostatin-1 is a specific RIP1 inhibitor and inhibits TNF-α-induced necroptosis (EC50: 490 nM in Jurkat cells).
Molecular Weight: 259, 33
