Product Overview
Neoandrographolide | T3884 | TargetMol Chemicals
CAS: 27215-14-1
Smiles: C[C@@]1(CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)CCC[C@@]2(C)[C@H](CCC3=CCOC3=O)C(=C)CC[C@H]12
Formula: C26H40O8
Pathway: Immunology/Inflammation|||Neuroscience
Target: NOS|||COX
Receptor: N/A
Bioactivity: Neoandrographolide has potent hypolipidemic effect and protects the cardiovascular without significant liver damage.Neoandrographolide has anti-inflammatory effect, might result from inhibition of iNOS and COX-2 expression through inhibiting p38 MAPKs activation.Neoandrographolide as chemosensitizer in S-Jurkat and X chromosome-linked inhibitor of apoptosis protein (XIAP)-overexpressing Jurkat cells, a model for chemoresistance.
Molecular Weight: 480, 598
