Product Overview
Neotuberostemonine | T4953 | TargetMol Chemicals
CAS: 143120-46-1
Smiles: CC[C@H]1[C@H]2OC(=O)[C@@H](C)[C@H]2[C@@H]2C[C@@H]([C@@H]3C[C@H](C)C(=O)O3)N3CCCC[C@H]1[C@H]23
Formula: C22H33NO4
Pathway: Immunology/Inflammation
Target: NOS
Receptor: N/A
Bioactivity: Neotuberostemonine (NTS) is one of the main antitussive alkaloids in the root of Stemona tuberosa Lour, it has a significant protective effect on bleomycin (BLM)-induced pulmonary fibrosis through suppressing the recruitment and M2 polarization of macrophages. Neotuberostemonine demonstrates antitussive properties in guinea pigs.
Molecular Weight: 375, 509