Product Overview
NEU-1045 | T28161 | TargetMol Chemicals
CAS: T28161
Smiles: FC1=CC(COC(C=C2)=CC=C2NC3=CC=NC(C3=C4)=CC=C4C5=CC=C(S(N6CCOCC6)(=O)=O)C=C5)=CC=C1
Formula: C32H28FN3O4S
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: NEU-1045 is a T. brucei proliferation inhibitor, and is a promising lead with cross-pathogen activity. NEU-1045 inhibited T. brucei, T. cruzi, and L. major proliferation with good potency (T. brucei EC50 = 0.37 μM; T. cruzi EC50 = 2.8 μM; L. major EC50 = 1.2 μM).
Molecular Weight: 569, 65
