Product Overview
NF-κB-IN-1 | T9105 | TargetMol Chemicals
CAS: 1227098-15-8
Smiles: O=C(/C=C/C(C=C1)=CC(OC)=C1OC)/C(C(/C=C/C(C=C2)=CC(OC)=C2OC)=O)=C/C(C=C3)=CC(OC)=C3O
Formula: C31H30O8
Pathway: NF-Κb
Target: IκB/IKK|||NF-κB
Receptor: N/A
Bioactivity: NF-κB-IN-1 is a potent NF-κB signaling pathway inhibitor. It is a 4-arylidene crucumin analogue. NF-κB-IN-1 directly inhibits IKK to block NF-κB activation. NF-κB-IN-1 effectively inhibits the viability of lung cancer cells and attenuates the clonogenic activity of A549 cells.
Molecular Weight: 530, 57
