Product Overview
NFPS | T16292 | TargetMol Chemicals
CAS: 405225-21-0
Smiles: CN(CCC(Oc1ccc(cc1)-c1ccccc1)c1ccc(F)cc1)CC(O)=O
Formula: C24H24FNO3
Pathway: Proteases/Proteasome
Target: Thrombin
Receptor: N/A
Bioactivity: NFPS exerts neuroprotection via glyR alpha1 subunit in the rat model of transient focal cerebral ischaemia and reperfusion. NFPS is a selective and non-competitive glycine transporter-1 (GlyT1) inhibitor (IC50s: 2.8 nM and 9.8 nM for hGlyT1 and rGlyT1, respectively).
Molecular Weight: 393, 458