Product Overview
NGB 2904 | T28167 | TargetMol Chemicals
CAS: 189060-98-8
Smiles: O=C(c(cc1)cc(C2)c1-c1c2cccc1)NCCCCN(CC1)CCN1c1cccc(Cl)c1Cl.Cl
Formula: C28H30Cl3N3O
Pathway: GPCR/G Protein|||Neuroscience|||Others
Target: Others|||Dopamine Receptor|||5-HT Receptor
Receptor: N/A
Bioactivity: NGB2904 is a potent and selective antagonist of dopamine D3 receptor (Ki values are 1.4, 217, 223, 642, > 5000, > 10000 and > 10000 nM for D3, D2, 5-HT2, α1, D4, D1 and D5 receptors respectively). NGB2904 potently antagonizes mitogenesis stimulated by quinpirole (IC50 = 6.8 nM).
Molecular Weight: 530, 92
