Product Overview
NHWD-870 | T36573 | TargetMol Chemicals
CAS: 2115742-03-3
Smiles: N/A
Formula: C29H29N7O
Pathway: Apoptosis|||Chromatin/Epigenetic
Target: Apoptosis|||Epigenetic Reader Domain
Receptor: N/A
Bioactivity: NHWD-870 is an effective and selective inhibitor of BET family bromodomain only binding to BRD2, BRD3, BRD4 (IC50 = 2.7 nM), and BRDT. NHWD-870 exhibits potent anti-tumor efficacies and suppresses cancer cell-macrophage interaction through the increase of tumor apoptosis and inhibition of tumor proliferation.
Molecular Weight: 491, 59
