Product Overview
Nigericin sodium salt | T3092 | TargetMol Chemicals
CAS: 28643-80-3
Smiles: [Na+].[H][C@@]1(C[C@H](C)[C@@]([H])(O1)[C@]1(C)CC[C@@]([H])(O1)[C@]1(C)C[C@@H](C)[C@]2(O1)O[C@H](C[C@H]1CC[C@H](C)[C@@H](O1)[C@@H](C)C([O-])=O)C[C@@H](OC)[C@H]2C)[C@@]1([H])O[C@@](O)(CO)[C@H](C)C[C@@H]1C
Formula: C40H67NaO11
Pathway: Immunology/Inflammation|||Membrane transporter/Ion channel|||Microbiology/Virology|||NF-Κb
Target: Potassium Channel|||NOD-like Receptor (NLR)|||Antibacterial|||Antibiotic|||NOD
Receptor: N/A
Bioactivity: Nigericin sodium salt is an antibiotic from Streptomyces hygroscopicus and is a NLRP3 activator.Nigericin sodium is a cationic ionophore that inhibits Golgi function and suppresses growth of gram positive bacteria. It also prevents viral activation and triggers activation of the NALP3 inflammasome.
Molecular Weight: 746, 94
