NITD-2 | T8886

NITD-2 | T8886 | TargetMol Chemicals

CAS: 1197896-79-9

Smiles: OC(=O)c1ccccc1NS(=O)(=O)c1cccc(c1)-c1cnn(Cc2ccccc2)c1

Formula: C23H19N3O4S

Pathway: Cell Cycle/Checkpoint|||DNA Damage/DNA Repair

Target: DNA/RNA Synthesis

Receptor: N/A

Bioactivity: NITD-2 is a dengue virus (DENV) polymerase inhibitor, inhibits the DENV RdRp-mediated RNA elongation. NITD-2 penetrates cell membrane poorly. Dengue virus (DENV) is the most prevalent mosquito- borne viral pathogen in humans. Neither vaccine nor antiviral therapy is currently available for DENV.

Molecular Weight: 433, 48