Product Overview
NLRP3-IN-9 | T28178 | TargetMol Chemicals
CAS: 88039-46-7
Smiles: CCOC(=O)C(=C)C(O)c1ccccc1Cl
Formula: C12H13ClO3
Pathway: Immunology/Inflammation|||NF-Κb
Target: NOD
Receptor: N/A
Bioactivity: NLRP3-IN-9 is an inhibitor of NLRP3 ATPase and caspase-1. NLRP3-IN-9 acts by irreversibly trapping thiol nucleophiles, which prevents both ATP- and nigericin-triggered pyroptosis of human THP-1 cells in a time- and concentration-dependent manner.
Molecular Weight: 240, 68
