Product Overview
NMK-TD-100 | T28179 | TargetMol Chemicals
CAS: 1252802-38-2
Smiles: COc1cc(cc(OC)c1OC)-c1nnc(s1)-c1c[nH]c2ccccc12
Formula: C19H17N3O3S
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: NMK-TD-100 is a microtubule modulating agent with anti-proliferative activity by disrupting microtubule functions through tubulin binding. NMK-TD-100 blocks mitosis and induces apoptosis in HeLa cells by binding to tubulin. Polymerization of tissue purified tubulin into microtubules was inhibited by NMK-TD-100 with an IC50 value of 17.5±0.35 µM.
Molecular Weight: 367, 42
