Product Overview
NNC052090 | T28183 | TargetMol Chemicals
CAS: 184845-43-0
Smiles: COc1ccccc1C1(O)CCN(CCCn2c3ccccc3c3ccccc23)CC1
Formula: C27H30N2O2
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: NNC052090 is a GABA uptake inhibitor that displays moderate selectivity for BGT-1 transporters with Ki values are 1.4, 15, 19 and 41 μM for hBGT-1, hGAT-3, hGAT-1 and hGAT-2 respectively. NNC052090 also displays affinity at α1- and D2-receptors with IC50 values are 266 and 1632 nM respectively.
Molecular Weight: 414, 549