Product Overview
NNMTi | T8760 | TargetMol Chemicals
CAS: 42464-96-0
Smiles: [I-].C[n+]1cccc2c(N)cccc12
Formula: C10H11IN2
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: NNMTi is a substrate site-targeting, selective nicotinamide N-methyltransferase (NNMT) inhibitor (IC50 = 1.2 μM; 50 μM SAM, 100 μM NCA) that reduces 3T3-L1 lipogenesis (EC50 = 30μM) and adipocytes 1-methylnicotinamide level (EC50 = 2.3 μM) without affecting related methyltransferases & enzymes in the NAD+ salvage pathway
Molecular Weight: 286, 116