Product Overview
Nocodazole | T2802 | TargetMol Chemicals
CAS: 31430-18-9
Smiles: COC(=O)Nc1nc2cc(ccc2[nH]1)C(=O)c1cccs1
Formula: C14H11N3O3S
Pathway: Angiogenesis|||Apoptosis|||Autophagy|||Cytoskeletal Signaling|||DNA Damage/DNA Repair|||Tyrosine Kinase/Adaptors
Target: Apoptosis|||Microtubule Associated|||Bcr-Abl|||Autophagy|||CRISPR/Cas9
Receptor: N/A
Bioactivity: Nocodazole is a synthetic inhibitor of microtubule polymerization, also inhibits Abl (IC50: 0.21 μM), Abl(E255K, IC50: 0.53 μM) and Abl(T315I, IC50: 0.64 μM) in cell-free assays. Nocodazole binds to beta-tubulin and disrupts microtubule assembly/disassembly dynamics.
Molecular Weight: 301, 32
