Product Overview
NoxA1ds acetate(1435893-78-9 free base) | TP1886L1 | TargetMol Chemicals
CAS: TP1886L1
Smiles:
Formula: C52H92N14O17
Pathway: Immunology/Inflammation
Target: NADPH-oxidase
Receptor: N/A
Bioactivity: NoxA1ds acetate is a potent and selective NADPH oxidase 1 (NOX1) inhibitor (IC50 : 20 nM). Exhibits selectivity for NOX1 over NOX2, NOX4, NOX5 and xanthine oxidase. Inhibits NOX1-derived O2- production in HT-29 human colon cancer cells. Attenuates VEGF-induced human pulmonary artery endothelial cell migration under hypoxic conditions in vitro.
Molecular Weight: 1185, 35
