Product Overview
NSC 663284 | T16357 | TargetMol Chemicals
CAS: 383907-43-5
Smiles: ClC1=C(NCCN2CCOCC2)C(=O)c2ncccc2C1=O
Formula: C15H16ClN3O3
Pathway: Membrane transporter/Ion channel|||Metabolism
Target: Calcium Channel
Receptor: N/A
Bioactivity: NSC 663284 is a cell-permeable and irreversible Cdc25 dual specificity phosphatase inhibitor (IC50 for Cdc25B2: 0.21 μM). NSC 663284 inhibits NSD2 (IC50 of 170 nM) through direct interaction with the catalytic SET domain (Kd of 370 nM). NSC 663284 displays mixed competitive kinetics against Cdc25A, Cdc25B(2), and Cdc25C with Ki values of 29, 95, and 89 nM, respectively.
Molecular Weight: 321, 76
