Product Overview
NU6027 | T6612 | TargetMol Chemicals
CAS: 220036-08-8
Smiles: Nc1nc(N)c(N=O)c(OCC2CCCCC2)n1
Formula: C11H17N5O2
Pathway: Cell Cycle/Checkpoint|||DNA Damage/DNA Repair|||PI3K/Akt/mTOR signaling
Target: ATM/ATR|||DNA-PK|||CDK
Receptor: N/A
Bioactivity: NU6027 is a potent ATR/CDK inhibitor, inhibits CDK1/2, ATR and DNA-PK with Ki of 2.5 μM/1.3 μM, 0.4 μM and 2.2 μM, enter cells more readily than the 6-aminopurine-based inhibitors.
Molecular Weight: 251, 29