Product Overview
NVP-ADW742 | T6079 | TargetMol Chemicals
CAS: 475488-23-4
Smiles: Nc1ncnc2n(cc(-c3cccc(OCc4ccccc4)c3)c12)C1CC(CN2CCCC2)C1
Formula: C28H31N5O
Pathway: Apoptosis|||Tyrosine Kinase/Adaptors
Target: Apoptosis|||IGF-1R
Receptor: N/A
Bioactivity: NVP-ADW742 is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-Abl and c-Kit.
Molecular Weight: 453, 59
