Product Overview
NVS-SM2 | T33764 | TargetMol Chemicals
CAS: 1562333-92-9
Smiles: CN(C1CC(C)(C)NC(C)(C)C1)c1ccc(nn1)-c1ccc(cc1O)-c1cn[nH]c1
Formula: C23H30N6O
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: NVS-SM2 is an effective small molecule splicing enhancer of SMN2 with oral activity. NVS-SM2 showed increased exon 7 inclusion and upregulated SMN protein expression in SMA fibroblasts and SMN cells Δ7 5025 mouse myoblasts.
Molecular Weight: 406, 534