NVS-SM2 | T33764

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TMC-T33764
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Product Overview

NVS-SM2 | T33764 | TargetMol Chemicals

CAS: 1562333-92-9

Smiles: CN(C1CC(C)(C)NC(C)(C)C1)c1ccc(nn1)-c1ccc(cc1O)-c1cn[nH]c1

Formula: C23H30N6O

Pathway: N/A

Target: N/A

Receptor: N/A

Bioactivity: NVS-SM2 is an effective small molecule splicing enhancer of SMN2 with oral activity. NVS-SM2 showed increased exon 7 inclusion and upregulated SMN protein expression in SMA fibroblasts and SMN cells Δ7 5025 mouse myoblasts.

Molecular Weight: 406, 534

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