Product Overview
Ogerin | T16378 | TargetMol Chemicals
CAS: 1309198-71-7
Smiles: Nc1nc(NCc2ccccc2)nc(n1)-c1ccccc1CO
Formula: C17H17N5O
Pathway: GPCR/G Protein|||Neuroscience|||Others
Target: Others|||5-HT Receptor|||Adenosine Receptor
Receptor: N/A
Bioactivity: Ogerin is a selective GPR68 positive allosteric modulator (pEC50: 6.83). Ogerin blocks recall in fear conditioning in mice. Ogerin displays inverse agonist and antagonist activity (Ki, 220 nM) at A2A receptor and weak antagonist activity (Ki, 736 nM) at 5-HT2B receptor.
Molecular Weight: 307, 357