Okadaic acid | T16381

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TMC-T16381
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Okadaic acid | T16381 | TargetMol Chemicals

CAS: 78111-17-8

Smiles: [H][C@]1(CC(C)=C[C@@]2(O[C@H](C[C@@](C)(O)C(O)=O)CC[C@H]2O)O1)[C@H](C)\C=C\[C@H]1CC[C@@]2(CC[C@@]3([H])O[C@]([H])([C@@H](O)C[C@H](C)[C@@]4([H])O[C@@]5(CCCCO5)CC[C@H]4C)C(=C)[C@@H](O)[C@]3([H])O2)O1

Formula: C44H68O13

Pathway: Others

Target: Others

Receptor: N/A

Bioactivity: Okadaic acid is a non-comepetitive, selective and reversible serine/threonine-specific protein phosphatases 1 (PP1), PP2A, and PP3 inhibitor (IC50s: 10-15 nM, 0.5 nM, and 4 nM, respectively). Okadaic acid is extracted from black sponges of the genus Halichondria. Okadaic acid eliminates metazoan symbionts/parasites by apoptosis.

Molecular Weight: 805, 015

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