Product Overview
ON123300 | T6920 | TargetMol Chemicals
CAS: 1357470-29-1
Smiles: CN1CCN(CC1)c1ccc(Nc2ncc3cc(C#N)c(=O)n(C4CCCC4)c3n2)cc1
Formula: C24H27N7O
Pathway: Angiogenesis|||Apoptosis|||Cell Cycle/Checkpoint|||Chromatin/Epigenetic|||JAK/STAT signaling|||PI3K/Akt/mTOR signaling|||Stem Cells|||Tyrosine Kinase/Adaptors
Target: FGFR|||c-RET|||JAK|||CDK|||PDGFR|||Src|||AMPK
Receptor: N/A
Bioactivity: ON123300 is a potent and multi-targeted kinase inhibitor for CDK4/Ark5/PDGFRĪ²/FGFR1/RET/Fyn (IC50: 3.9/5/26/26/9.2/11 nM).
Molecular Weight: 429, 528