Product Overview
Onjisaponin B | TN1140 | TargetMol Chemicals
CAS: 35906-36-6
Smiles: COc1ccc(\C=C\C(=O)O[C@@H]2[C@H](C)O[C@H](OC(=O)[C@@]34CCC(C)(C)C[C@@H]3C3=CC[C@@H]5[C@]6(C)C[C@H](O)[C@H](O[C@H]7O[C@H](CO)[C@@H](O)[C@@H](O)[C@H]7O)[C@](C)([C@@H]6CC[C@@]5(C)C3(CO)CC4)C(O)=O)[C@@H](O[C@H]3O[C@H](C)[C@@H](O[C@H]4OC[C@@H](O[C@H]5O[C@H](CO)[C@@H](O)[C@@H](O)[C@H]5O)[C@@H](O)[C@H]4O)[C@@H](O)[C@H]3O)[C@@H]2O[C@H]2O[C@H](C)[C@H](O)[C@H](O)[C@@H]2O)cc1
Formula: C75H112O35
Pathway: Autophagy|||PI3K/Akt/mTOR signaling
Target: AMPK|||mTOR|||Autophagy
Receptor: N/A
Bioactivity: Onjisaponin B induces autophagy via the AMPK-mTOR signaling pathway, increases the NGF level and accelerates both the removal of mutant huntingtin and A53T α±-synuclein, it may have potential therapeutic effects on Parkinson disease, Alzheimer disease and Huntington disease.
Molecular Weight: 1573, 686
