Product Overview
ONO-0300302 | T28245 | TargetMol Chemicals
CAS: 856689-51-5
Smiles: COc1cc(cc(OC)c1C)[C@@H](O)[C@@H](CC1Cc2ccccc2C1)Cn1ccc(CCC(O)=O)c1
Formula: C29H35NO5
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: ONO-0300302 is a slow tight binding LPA1 antagonist (IC50: 0.16 nM) used to treat Benign Prostatic Hyperplasia. ONO-0300302 inhibits significantly an LPA-induced increase of intraurethral pressure (IUP) in rat (3 mg/kg, p.o.) and dog (1 mg/kg, p.o.) over 12 h.
Molecular Weight: 477, 601
