ONO-0300302 | T28245

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€100.00
SKU:
TMC-T28245
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Product Overview

ONO-0300302 | T28245 | TargetMol Chemicals

CAS: 856689-51-5

Smiles: COc1cc(cc(OC)c1C)[C@@H](O)[C@@H](CC1Cc2ccccc2C1)Cn1ccc(CCC(O)=O)c1

Formula: C29H35NO5

Pathway: N/A

Target: N/A

Receptor: N/A

Bioactivity: ONO-0300302 is a slow tight binding LPA1 antagonist (IC50: 0.16 nM) used to treat Benign Prostatic Hyperplasia. ONO-0300302 inhibits significantly an LPA-induced increase of intraurethral pressure (IUP) in rat (3 mg/kg, p.o.) and dog (1 mg/kg, p.o.) over 12 h.

Molecular Weight: 477, 601

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