Product Overview
Ono 1301 | T28240 | TargetMol Chemicals
CAS: 176391-41-6
Smiles: CC1=C(CCO\N=C(\c2ccccc2)c2cccnc2)c2cccc(OCC(O)=O)c2CC1
Formula: C27H26N2O4
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Ono 1301 is a prostaglandin I2 mimetic coumpound with inhibitory activity against thromboxane A2 synthase. Ono 1301 suppresses pancreatic fibrosis in the DBTC-induced CP model by inhibiting monocyte activity not only with induction of HGF but also by Ono 1301 itself. It also works through promoting synthesis of hepatocyte growth factor and increasing cyclic AMP concentration via IP-receptor signaling.
Molecular Weight: 442, 515
